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We could probably have found room for Gwen Stacy and Miles Morales in a non-Spider-Man specific set, but there wouldnt have been room for Aunt May. McCall says that designing for a Universes Beyond set flips the worldbuilding on its head, in that a typical Magic set needs its cards to lay the groundwork of its location and setting while also being fun to play with in order to get players on board, whereas most people already have some familiarity with a character like Spider-Man

This mini-expansion has around a third of the cards that Genetic Apex does

GX chapter 6: "Miss Duel Academy" Yu-Gi-Oh

If you want to open boxes for fun without paying a premium, OP-14 is your best bet right now

Nintendo understands this very well